Abstract Background Photodynamic therapy (PDT) is a promising therapeutic modality that can convert oxygen into cytotoxic reactive oxygen species (ROS) via photosensitizers to halt tumor growth.However, hypoxia and the unsatisfactory accumulation of photosensitizers in tumors severely diminish the therapeutic effect of PDT.In this study, a multista
Aim Periodontitis is a site-specific, chronic disease treated by non-surgical debridement of subgingival plaque.We aimed to determine the microbiome of sites that did not respond to this treatment (NR) SCREEN compared with paired good responding (GR) sites before and after treatment.Materials and methods In a longitudinal cohort study, clinical par
Antimicrobial resistance (AMR) is a risk for public health that requires management in a One Health perspective, including humans, animals, and the environment.The food production chain has been identified as a possible route of transmission of AMR bacteria to humans.The most critical issue regards resistance to the Critically Important Antimicrobi
Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family.These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA.The rapid expansion of protein domain repeats is assumed to have evolved through internal